A good fit if you…
- Want NAD+ support without a needle
- Prefer a daily routine over a weekly dose
- Travel often or live the on-the-go life
- Want a starter protocol before adding the injectable
- Are looking for a longevity-focused baseline
Home Treatments NAD+ Spray
New
Energy & longevity · Oral spray
NAD+ Spray.
Daily NAD+ support, no needle. A sublingual spray you take in the morning to keep cellular energy at baseline.
$279
- DailySublingual
- 2-3 days Clinical review
- 5-7 days Cold-chain ship
Pause or cancel anytime
What it does
NAD+, daily.
NAD+, daily.
No needle.
01.
Sublingual NAD+ skips the gut. Held under the tongue, NAD+ absorbs through the oral mucosa straight into capillary circulation — bypassing first-pass metabolism that breaks down oral capsules.
02.
Daily compliance is the unlock. NAD+ is dose-frequency-sensitive — small daily inputs out-perform sporadic larger ones for most patients. The spray is the simplest way to make daily happen.
03.
Pairs cleanly with the injectable protocol. Many use the spray as daily upkeep between weekly clinical injections, keeping cellular pools stable on travel days or off-cycle weeks.
The protocol
Built around the molecule, not around marketing.
Your protocol is written by a US-licensed clinician based on your intake and goals. Compounded by a US-licensed pharmacy under USP <797> sterile standards. Cold-chain shipped to your door.
Active ingredient
Nicotinamide Riboside / NAD+ precursor blendSublingual oral spray, compounded
Route
Sublingual sprayHeld under the tongue 30-60 seconds
Frequency
Once dailyMost patients dose with morning routine
Dosing
2-4 sprays dailyAdjusted by clinician based on response
Supply
30-day supply per shipmentOne bottle, ~30 doses per fill
Shipping
Cold-chain, tracked, US-onlyShelf-stable shipping, no cold chain
What to expect
Your first 90 days,
Your first 90 days,
in plain language.
Two sprays under the tongue, twice a day. Effects are subtle at first and compound across weeks.
Week 01–02
Daily habit.
Twice-daily dosing builds the routine. Most users notice nothing dramatic in the first 14 days — that's expected.
Week 03–06
First signal.
Mornings feel less leaden. Post-meal energy dips soften. Cumulative dose, not a single dose, drives the lift.
Month 02–04
Compounding.
Cellular NAD+ stays topped up between meals. Mood baseline lifts; sleep often improves alongside.
Month 04+
Maintenance.
Continue twice daily indefinitely or pair with a weekly injectable for accelerated effect.
Is this right for me
Built for some bodies, not for others.
Eligibility is determined by a US-licensed clinician based on your intake.
Probably not for you if…
- Are pregnant, nursing, or planning pregnancy
- Have an active cancer diagnosis
- Have known sensitivity to nicotinamide compounds
- Want the strongest cellular dose — see NAD+ Injectable instead
The case
2× / day
sublingual sprays — the simplest, most-compliant way to keep cellular NAD+ topped up between meals. Daily input compounds far faster than sporadic loading.
Sublingual bioavailability data: Conze et al., 2019; clinical compliance literature ongoing
Reviewed by clinicians
Every prescription starts with a US-licensed clinician.
US-licensed pharmacy
One pharmacy, one chain of custody, every batch tested.
Discreet US shipping
Cold-chain monitored, plain box, tracked nationwide.
Pause or cancel anytime
Adjust dosing, pause, or cancel from your portal.
Common questions
FAQ — NAD+ Spray.
How is NAD+ Spray different from the injectable?
The spray is sublingual and dosed daily. The injectable is subcutaneous and dosed weekly. The spray is a quieter, steady-state delivery; the injectable produces a stronger weekly peak. Many patients use both.
Can I take this with food or coffee?
Yes. Most patients dose it with their morning routine. Hold the spray under your tongue for 30-60 seconds before swallowing for full absorption.
Does it taste bad?
It has a mild herbal note. Most patients find it neutral or slightly minty. Adjusts quickly.
Can I pause or cancel?
Yes. Pause, skip a month, switch protocols, or cancel anytime from your portal. No phone tag, no fees.
How is this prescribed legally?
Endeavor's NAD+ Spray is a prescription compounded medication. A US-licensed clinician reviews your intake before any prescription is written, and your medication is compounded by a US-licensed pharmacy.
The recommended stack
What clinicians pair
What clinicians pair
with NAD+ Spray.
The spray covers daily upkeep. The pairings below cover the loading and the defensive flank.